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When people die from overdosing on a drug, the drug is usually an opioid and often heroin. In the United States, approximately 1.6 percent of people have used heroin at some point, with 950,000 using it in the last year. The total number of heroin users worldwide as of 2015 is believed to have increased in Africa, the Americas, and Asia since 2000. An estimated 17 million people as of 2015 use opiates, of which heroin is the most common, and opioid use resulted in 122,000 deaths. A heroin overdose may be treated with naloxone. Medications can include buprenorphine, methadone, or naltrexone. Treatment of heroin addiction often includes behavioral therapy and medications. It typically appears in the form of a white or brown powder. When given by injection into a vein, heroin has two to three times the effect of a similar dose of morphine. After a history of long-term use, opioid withdrawal symptoms can begin within hours of the last use. Side effects of use by injection can include abscesses, infected heart valves, blood-borne infections, and pneumonia. Ĭommon side effects include respiratory depression (decreased breathing), dry mouth, drowsiness, impaired mental function, constipation, and addiction. The onset of effects is usually rapid and lasts for a few hours. In a clinical context the route of administration is most commonly intravenous injection it may also be given by intramuscular or subcutaneous injection, as well as orally in the form of tablets. It is typically injected, usually into a vein, but it can also be smoked, snorted, or inhaled. Diamorphine is used medically in several countries to relieve pain, such as during childbirth or a heart attack, as well as in opioid replacement therapy. Medical grade diamorphine is used as a pure hydrochloride salt which is distinguished from black tar heroin, a variable admixture of morphine derivatives-predominantly 6-MAM (6-monoacetylmorphine), which is the result of crude acetylation during clandestine production of street heroin. Heroin, also known as diacetylmorphine and diamorphine among other names, is an opioid used as a recreational drug for its euphoric effects.